2-(4-chloro-3-cyanophenyl)-2,2-difluoroacetic acid - Names and Identifiers
2-(4-chloro-3-cyanophenyl)-2,2-difluoroacetic acid - Introduction
2-(4-choro-3-cyanophenyl)-2,2-difluoroacetic acid is an organic compound with the chemical formula C9H5ClF2NO2.
Nature:
-Appearance: Colorless solid
-Melting point: 105-108 degrees Celsius
-Boiling point: 332 degrees Celsius
-Density: 1.501g/cm3
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol and chloroform
Use:
2-(4-choro-3-cyanophenyl)-2,2-difluoroacetic acid has certain application value:
-As a drug intermediate: It can be used to synthesize biologically active compounds or drugs.
-As a chemical reagent: It can be used in organic synthesis reactions, for example, as a carboxylic acid protective agent, Catalyst, etc.
Method:
2-(4-choro-3-cyanophenyl)-2,2-difluoroacetic acid is usually synthesized by the following steps:
1.4-chloro -3-cyanobenzeneboronic acid and 2,2-difluoroacetyl fluoride are reacted to obtain the target product under alkaline conditions.
Safety Information:
The safety information of 2-(4-chloroo-3-cyanophenyl)-2,2-difluoroacetic acid is not complete and may be toxic to the human body. When handling, wear suitable personal protective equipment and follow the safe handling of chemicals. Avoid contact with oxidants and high temperatures during use or storage. In case of inhalation, contact or ingestion, seek medical attention immediately and bring details of the compound with you.
Last Update：2024-04-09 02:00:51